[The influence of nicotine on the density of collagen in cutaneous scars in rats].

Objective: To study the inflammatory reaction and deposition of collagen in the healing of cutaneous injuries under the influence of nicotine.

Methods: The scars of abdominal injuries in rats were analyzed, which had been treated with nicotine, 2 mg/kg/d, and compared with those of control rats. Treatment was begun seven days prior to operation and was maintained for seven or fourteen days after surgery.

Effects of hyperglycemia and aging on the healing of colonic anastomoses in rats.

Introduction: Despite the significant advances in the knowledge of the healing process, there is a limited number of studies demonstrating the relationships of this healing with ageing and elevated levels of glycemia.

Purpose: To evaluate the effects of ageing and hyperglycemia on the healing of colonic anastomosis.

Methods: 138 young and old male rats were utilized.