Expanding the Toolbox for Genetic Manipulation in : RNAi-Mediated Silencing and CRISPR/Cas9-Mediated Disruption of a Polyketide Synthase Gene Involved in Red Pigment Production in .

Fungi belonging to the genus have garnered increasing attention in recent years. One of the members of the genus, , has been identified as the causal agent of a severe bat disease. Simultaneously, the knowledge of species has expanded, in parallel with the increased availability of genome sequences.

Pr Affects the Production of Roquefortine C, Mycophenolic Acid, and Andrastin A in , but It Has Little Impact on Asexual Development.

The regulation of fungal specialized metabolism is a complex process involving various regulators. Among these regulators, LaeA, a methyltransferase protein originally discovered in spp., plays a crucial role.

Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution.

Gibberellins (GAs) are crucial phytohormones involved in many aspects of plant growth and development, including plant-microbe interactions, which has led to GA production by plant-associated fungi and bacteria as well. While the GA biosynthetic pathways in plants and fungi have been elucidated and found to have arisen independently through convergent evolution, little has been uncovered about GA biosynthesis in bacteria. Some nitrogen-fixing, symbiotic, legume-associated rhizobia, including Bradyrhizobium japonicum-the symbiont of soybean-and Sinorhizobium fredii-a broad-host-nodulating species-contain a putative GA biosynthetic operon, or gene cluster.