Publications by authors named "Mariana Medina Medeiros"
Leishmaniases affect millions of people around the world, caused by Leishmania parasites. Leishmania are transmitted by female sandflies from Phlebotominae subfamily during their blood meals. In mammals, promastigotes are phagocytosed mainly by macrophages, differentiate into amastigotes and multiply.
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- Carbohydrates, specifically sialic acids, are essential components of cell surfaces that play significant roles in cellular communication and pathogen survival.
- More than 20 pathogens can utilize host-derived sialic acids to enhance their own survival and evade immune responses.
- This review examines the contributions of sialic acids, Siglecs, and Neuraminidase 1 in various pathogenic infections, highlighting their structural diversity and functional implications in host-pathogen interactions.