Effects of Zinc and N-Acetylcysteine in Damage Caused by Lead Exposure in Young Rats.

This study investigated the toxicity of rats exposed to lead acetate (AcPb) during the second phase of brain development (8-12 days postnatal) in hematological and cerebral parameters. Moreover, the preventive effect of zinc chloride (ZnCl) and N-acetylcysteine (NAC) was investigated. Pups were injected subcutaneously with saline (0.

Inorganic mercury exposure in drinking water alters essential metal homeostasis in pregnant rats without altering rat pup behavior.

The aim of this work was to investigate the effects of HgCl exposure in the doses of 0, 10 and 50μg Hg/mL in drinking water during pregnancy on tissue essential metal homeostasis, as well as the effects of HgCl exposure in utero and breast milk on behavioral tasks. Pregnant rats exposed to both inorganic mercury doses presented high renal Hg content and an increase in renal Cu and hepatic Zn levels. Mercury exposure increased fecal Hg and essential metal contents.