Publications by authors named "Mariana Freitas-de Aguiar"
Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer.
Adv Rheumatol
August 2024
Background: Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA.
View Article and Find Full Text PDFThe pathogenesis of Takayasu arteritis (TAK) is poorly understood and no previous studies have analyzed monocytes in TAK. This study evaluated monocyte subsets and monocyte-related chemokines in the peripheral blood of TAK patients and healthy controls (HC). Monocyte subsets were identified as classical (CD14CD16), intermediate (CD14CD16), and non-classical (CD14CD16) in the peripheral blood.
View Article and Find Full Text PDFArticle Synopsis
- A study was conducted on 66 elderly patients with Takayasu's arteritis (TAK) to assess how disease progression and treatment outcomes vary with age.
- Patients were categorized into four age groups, revealing that as age increased, the duration of the disease was longer, and there was a decrease in the use of prednisone and immunosuppressive drugs.
- Results indicated that older patients had a greater impairment in functional status, suggesting that this decline may be related to factors associated with aging rather than the disease itself.
Distribution of monocytes subpopulations in the peripheral blood from patients with Behçet's disease - Impact of disease status and colchicine use.
Clin Immunol
October 2021
The innate immune response has a predominant role in Behçet's disease (BD) pathogenesis, but few studies have assessed monocytes in BD. This study aims to evaluate the profile of monocytes subsets in the peripheral blood of BD patients and healthy controls (HC). Monocytes subsets were identified as classical (CD14CD16), intermediate (CD14CD16), and non-classical (CD14CD16) subsets.
View Article and Find Full Text PDFBackground: The Indian Takayasu Clinical Activity Score (ITAS2010) was developed in 2010 as an assessment tool for disease activity in patients with Takayasu arteritis (TA). It has since been widely used in different studies and in clinical practice for the management of patients with TA. The present study aims to translate the ITAS2010 into Brazilian Portuguese language and to validate it for use in clinical practice in Brazil.
View Article and Find Full Text PDFIntroduction And Objectives: Cryoglobulinemia is one of the most frequent extrahepatic manifestations of chronic hepatitis C virus (HCV) infection and it may evolve to cryoglobulinemic vasculitis (CryoVas) which is a systemic vasculitis that affects small-sized vessels. The objective of this study was to evaluate the prevalence of cryoglobulinemia and CryoVas in HCV patients in São Paulo, Brazil.
Materials And Methods: A cross-sectional study was conducted and included sixty-eight viremic HCV patients, without HIV or hepatitis B coinfection.