Publications by authors named "Mariana Ferreira Dos Anjos"
Article Synopsis
- Intestinal mucositis is a harmful side effect caused by cancer treatments like irinotecan, leading to significant mucosal damage; this research explores luteolin as a possible preventive treatment.
- In mouse experiments, luteolin demonstrated effectiveness in reducing symptoms of mucositis, including weight loss and diarrhoea, while also protecting intestinal tissue from damage and oxidative stress.
- The study concludes that luteolin could enhance cancer treatment by preventing intestinal mucositis without affecting the effectiveness of irinotecan, potentially improving patient compliance and outcomes in cancer therapy.
The treatment of chronic pain remains a challenge for clinicians worldwide, independent of its pathogenesis. It motivates several studies attempting to discover strategies to treat the disease. The in silico analysis using molecular docking approach demonstrated that the phthalimide N-(4methyl-phenyl)-4-methylphthalimide (MPMPH-1) presented high affinity to adenylyl-cyclase enzyme (AC).
View Article and Find Full Text PDFIpomoea pes-caprae (L.) R. Br (Convolvulaceae) relieved nociception and inflammation in mice - A topical herbal medicine against effects due to cnidarian venom-skin contact.
J Ethnopharmacol
March 2017
Ethnopharmacological Relevance: Ipomoea pes-caprae is known as bayhops, beach morning glory or goat's foot, and in Brazil as salsa-de-praia. Its leaves are used in worldwide folk medicine for the relief of jellyfish-stings symptoms. The literature only reports the neutralizing effects of nonpolar plant derived over jellyfish venoms, without validating the popular use or exploring the mechanism of action.
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