Publications by authors named "Mariana Dicugno"
Aim: To assess residual diuresis and diverse variables according to body mass index (BMI).
Methods: Cross-sectional study (n = 57), with 3 groups. Group A: BMI < 25, n = 22; Group B: BMI 25-30, n = 15; Group C: BMI > 30, n = 20.
Article Synopsis
- The study compared different methods for estimating glomerular filtration rate (GFR) and monitoring kidney disease progression, specifically using creatinine, cystatin, and CKD-EPI equations against (99m)Tc-DTPA scintigraphy in 300 subjects.
- Results showed that CKD-EPI equations had the highest correlation with (99m)Tc-DTPA for GFR measurement, particularly in patients with GFR < 60 mL/min.
- The study concluded that cystatin-based equations were more effective in correlating with (99m)Tc-DTPA across all stages of reduced GFR and that proteinuria had significant associations with cystatin levels.
Unlabelled: Procalcitonin (PCT) has emerged as a marker of infection, a frequent complication in hemodialysis (HD). We analyzed PCT levels in chronic non-acutely infected HD subjects, assessed its correlation with inflammatory and nutritional markers and propose a PCT reference value for non-infected HD patients. In an observational cross-sectional study, 48 chronic HD patients and 36 controls were analyzed.
View Article and Find Full Text PDFBackground: Certain adipokines exert direct effects on proteinuria, a cardiovascular risk factor ignored in hemodialysis. We measured different adipokines according to body mass index (BMI) in relation to proteinuria.
Methods: Patients numbered 57: group A (GA), BMI<25, n = 22; GB, BMI 25-30, n = 15; and GC, BMI > 30, n = 20.
Proteinuria: an ignored marker of inflammation and cardiovascular disease in chronic hemodialysis.
Int J Nephrol Renovasc Dis
October 2012
Background: Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis (HD) patients, the main etiologies being diabetes and hypertension. Cardiac and inflammatory biomarkers are usually employed to assess risk or damage, or during follow-up. Proteinuria is considered a strong predictor of morbidity, a cause of inflammation, oxidative stress, hemodynamic alteration, and progression of chronic kidney disease.
View Article and Find Full Text PDFArticle Synopsis
- - Adiponectin levels show varying cardiovascular effects based on body mass index (BMI), with higher levels linked to increased cardiovascular risk in nonobese individuals, while obese patients may have lower mortality despite low adiponectin.
- - The study analyzed 52 chronic hemodialysis patients divided into three BMI groups, revealing significant correlations between adiponectin and other markers like Pro-BNP and troponin T, as well as shifts in nutritional status and insulin resistance as BMI changes.
- - Results indicate that low-BMI individuals had worse nutritional status and higher levels of Pro-BNP and adiponectin, while obesity led to a hypoadiponectinemia that promotes harmful cardiac adaptations, suggesting adiponectin's
Background: We assessed the relationship between pro-brain natriuretic peptide (pro-BNP), troponin T (TropT) and nutritional status.
Methods: A total of 48 chronic hemodialysis patients were grouped according to the presence [group A (GA); n = 24] or not [group B (GB)] of cardiovascular disease.
Results: Compared to GB subjects, GA subjects were older, had been on hemodialysis for a longer period and had higher prevalences of vascular grafts, hypertension and elevated C-reactive protein (CRP) [GA vs.