Publications by authors named "Mariana C Cabatu"
Background: In diabetic kidney disease, high glucose damages specialized cells called podocytes that filter blood in the glomerulus. In vitro culture of podocytes is crucial for modeling of diabetic nephropathy and genetic podocytopathies and to complement animal studies. Recently, several methods have been published to derive podocytes from human-induced pluripotent stem cells (iPSCs) by directed differentiation.
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- * In a study involving one-day-old rats, those that experienced a heart attack showed a significant drop in heart function initially, but by three weeks, their heart function had returned to levels similar to those that did not have heart attacks.
- * The presence of new heart cells was confirmed in the injured area of the hearts, suggesting that newborn rats have a natural ability to grow new heart muscle after injury, which could one day help treat heart conditions in adults.