Complex lymphatic malformations in pediatrics: a review of treatment options.

Introduction: Lymphatic malformations (LMs) are low-flow lesions resulting from abnormalities in the development of lymphatics. The management of these lesions is complex and involve the collaboration of many specialties. The purpose of this review is to summarize current knowledge regarding the different therapeutic options used in complex lymphatic malformations, analyzing their indications, efficacy and complications.

Microcurrent stimulates cell proliferation and modulates cytokine release in fibroblast cells.

Aims: To analyse the effects of microcurrent on L929 fibroblast cell culture.

Methods: Cells were cultivated in six-well plates at densities of 5×10, 1×10, 3×10 and 5×10 cells/well to determine the best plating density. Subsequently, two methods of current application were tested: with a paper cone coupled to the electrode (M1) and with the electrode directly inside the well (M2).

Perinatal outcome after prenatal diagnosis of placental chorioangioma.

Objective: To review the prenatal complications, management, and perinatal outcome in pregnancies complicated by placental chorioangioma.

Methods: Cases of placental chorioangioma diagnosed prenatally as part of a prospective, multicentric program for fetal diagnosis and therapy were identified. All cases were evaluated with color flow imaging.