Publications by authors named "Mariana Boechat de Abreu"
Article Synopsis
- Cylindrospermopsin (CYN) is a harmful cyanotoxin that poses increasing risks to human health, particularly affecting the lungs.
- In a study using male BALB/c mice, the effects of CYN were assessed alongside treatments with the anti-inflammatory drug dexamethasone to see if it could alleviate the damage caused by CYN.
- Results showed that CYN led to worsened lung mechanics and inflammation, but treatment with dexamethasone helped to reverse some of these negative effects.
Variable Ventilation Associated With Recruitment Maneuver Minimizes Tissue Damage and Pulmonary Inflammation in Anesthetized Lung-Healthy Rats.
Luciana Moisés Camilo Gabriel Casulari Motta-Ribeiro Mariana Barcellos de Ávila Luis Felipe Santos Cruz Paula Mariana Boechat de Abreu
Anesth Analg
September 2018
Background: Recruitment maneuver and positive end-expiratory pressure (PEEP) can be used to counteract intraoperative anesthesia-induced atelectasis. Variable ventilation can stabilize lung mechanics by avoiding the monotonic tidal volume and protect lung parenchyma as tidal recruitment is encompassed within the tidal volume variability.
Methods: Forty-nine (7 per group) male Wistar rats were anesthetized, paralyzed, and mechanically ventilated.