Publications by authors named "Marian Montiel Peralta"
Pilot-scale co-precipitation synthesis of a novel active ingredient made of ultrasmall iron (oxyhydr)oxide nanoparticles for the treatment of hyperphosphatemia.
Magdalena Teresa Spicher Sebastian Patrick Schwaminger Daniela von der Haar-Leistl Marian Montiel Peralta Georgina Mikacevic
RSC Adv
May 2024
Article Synopsis
- Co-precipitation is a simple and commonly used method for creating iron (oxyhydr)oxide nanoparticles, but its sensitivity to process changes has limited production scale to 1.2 L so far.
- This study successfully scaled up the co-precipitation method to produce 100 L of nanoparticles while maintaining synthesis efficacy and yield across various scales, with only minor variations in component content.
- Characterization techniques showed that while the iron (oxyhydr)oxide cores became smaller, there were no significant structural changes, confirming that high-yield, ultrasmall nanoparticles can be produced on a larger scale.