The MDR1/ABCB1 gene rs 1045642 polymorphism in colorectal cancer.

Introduction: Colorectal cancer (CRC) is one of the most frequently diagnosed tumors in Western countries. CRC is a heterogeneous group of tumors with regards to its molecular pathogenesis and genetic factors. Both genetic variations and anthropometric factors may affect morbidity in CRC patients.

[Non-obstetric surgery during pregnancy].

Diseases of the abdomen (cholecystitis, appendicitis, adnexal masses), although they rarely occur during pregnancy, pose a threat both to the gravid women and the fetus. We attempt to systemize current knowledge on the topic and to outline some diagnostic and therapeutic trends. Appendicitis is very difficult to diagnose during pregnancy.