Publications by authors named "Mariama Colley"
Article Synopsis
- This study investigates the roles of gut microbiota, pathogens, and hormones in severe acute malnutrition (marasmus SAM) and moderate acute malnutrition (MAM) in young children in rural Gambia.
- Researchers used association networks to analyze how these factors contribute to the severity of acute malnutrition.
- Findings indicate that children with marasmus SAM have unique gut microbiome profiles and lower microbial diversity, along with specific interactions between gut bacteria and energy-regulating hormones, which underscores the need for further research for new interventions.
Background: Malnourished children show variable growth responses to nutritional rehabilitation. We aimed to investigate whether these differences could be explained by variations in growth and energy-regulating hormones.
Methods: Quasi-experimental study: Children aged 6-24 months in rural Gambia were recruited to controls if weight-for-height z-score (WHZ) > -2 (n = 22), moderate acute malnutrition if WHZ < -2 and > -3 (n = 18) or severe acute malnutrition if WHZ < -3 (n = 20).