The study focused on estimating the household secondary infection attack rate (hSAR) of SARS-CoV-2 using data from WHO protocols and involved a systematic review and meta-analysis of relevant articles published from December 2019 to July 2021.
Out of nearly 10,000 records, 80 articles were selected, with 62 included in the main analysis, revealing hSAR estimates that varied widely from 2% to 90%, indicating significant heterogeneity in the results.
The findings highlight the importance of standardizing methodologies in future investigations to improve pandemic preparedness and response for COVID-19 and other respiratory viruses.