Publications by authors named "Mariam Al Beloushi"
Viruses are the most common congenital infections in humans and an important cause of foetal malformations, neonatal morbidity, and mortality. The effects of these infections, which are transmitted in utero (transplacentally), during childbirth or in the puerperium depend on the timing of the infections. These vary from miscarriages (usually with infections in very early pregnancy), congenital malformations (when the infections occur during organogenesis) and morbidity (with infections occurring late in pregnancy, during childbirth or after delivery).
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- The SARS-CoV2 virus, first reported in December 2019, led to a global pandemic declared by WHO in March 2021, resulting in over 6.5 million deaths, likely an underestimate of the true toll.
- The rapid development and global adoption of vaccines changed the dynamics of the pandemic, utilizing various platforms like mRNA for the first time in humans, which has important implications for healthcare professionals regarding effectiveness and safety.
- While current vaccines have shown safety in reproduction and pregnancy, ongoing monitoring for rare adverse effects remains crucial, and the need for repeat vaccinations is anticipated, although the specifics of frequency and dosage are still uncertain.
Human papillomavirus (HPV) in pregnancy - An update.
Eur J Obstet Gynecol Reprod Biol
September 2021
Human papilloma viruses (HPV) are small epitheliotropic DNA viruses, of which there are 200 genotypes, 40 of which are known to cause genital infections and are also oncogenic. HPV is the most common sexually transmitted infection. Clinical features vary from asymptomatic (identified at routine cervical cancer screening) to large lesions on the vulva, vagina, cervix and some extragenital sites.
View Article and Find Full Text PDFSevere acute respiratory syndrome (SARS) coronavirus-2 infection (COVID-19) in pregnancy - An overview.
Eur J Obstet Gynecol Reprod Biol
August 2021
The novel severe acute respiratory syndrome (SARS) coronavirus-2 which causes COVID-19 disease results in severe morbidity and mortality especially in vulnerable groups. Pregnancy by virtue of its physiological and anatomical adaptations increases the risk of severe infections especially those of the respiratory tract. This single stranded RNA virus is transmitted by droplets as well as soiled fomites.
View Article and Find Full Text PDFPregnancy is a unique period in which several changes occur in the mother, to ensure that the semiallograft fetus is not rejected. Some of these changes decrease the immunity of the mother to infections. As such, some infections in pregnancy which may not ordinarily cause severe symptoms can be more severe in the mother and importantly some of these infections pose a danger to the fetus either directly or indirectly.
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