Publications by authors named "Marialuisa Ferraro"
Article Synopsis
- A pharmacovigilance study analyzed reports of myocarditis and pericarditis associated with mRNA COVID-19 vaccines in the VAERS database from 1990 to July 2021, finding significant cases linked primarily to these vaccines.
- The majority of reported cases were in young males, particularly after the second vaccine dose, but the overall risk of these heart conditions was much lower compared to the risks from COVID-19 infection and common viral myocarditis.
- Compared to smallpox vaccines, the study found that mRNA COVID-19 vaccines had a significantly lower probability of causing myocarditis or pericarditis.
An accelerated rate of fat recovery (catch-up fat) and insulin resistance are characteristic features of weight recovery after caloric restriction, with implications for the pathophysiology of catch-up growth and weight fluctuations. Using a previously described rat model of weight recovery in which catch-up fat and skeletal muscle insulin resistance have been linked to suppressed thermogenesis per se, we investigated alterations in mitochondrial energetics and oxidative stress in subsarcolemmal (SS) and intermyofibrillar (IMF) skeletal muscle mitochondria. After 2 weeks of semistarvation followed by 1 week of refeeding, the refed rats show persistent and selective reductions in SS mitochondrial mass (assessed from citrate synthase activity in tissue homogenate and isolated mitochondria) and oxidative capacity.
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