Publications by authors named "Marialaura Bisegna"
Br J Haematol
November 2024
Article Synopsis
- ATRA and ATO are the main treatments for low to medium risk acute promyelocytic leukaemia (APL), but many patients (60%) can have a side effect called leucocytosis, which means very high white blood cell counts.
- Researchers studied 65 APL patients and found that those with lower levels of important blood proteins (like fibrinogen) and higher amounts of cancer cells in their bone marrow were more likely to have leucocytosis when treated with ATRA and ATO.
- Leucocytosis can lead to other serious problems, so doctors need to keep a close eye on patients with these risk factors to help prevent issues and give extra treatments if needed.
