Synopsis of recent research by authors named "Mariah J Prom"
- Mariah J Prom's recent research focuses on various therapeutic approaches and biomarkers for neuromuscular diseases, particularly Duchenne muscular dystrophy (DMD) and myotubular myopathy, highlighting the critical need for effective treatments and diagnostics in these progressive conditions.
- Her studies explore novel gene therapies, such as resamirigene bilparvovec for X-linked myotubular myopathy, and indicate potential disease biomarkers, like HMGB1, to enhance understanding of inflammatory responses and treatment efficacy in DMD models.
- Prom also investigates the underlying pathophysiology of muscle diseases through mouse models, examining metabolic pathways and mitochondrial function in conditions like nemaline myopathy, thereby elucidating common pathological processes despite genetic variability.
