Publications by authors named "Mariah C Meyer"
Article Synopsis
- Chronic kidney disease significantly impacts global health, particularly among individuals of African ancestry and those in the Americas, who are often excluded from genetic studies.
- A comprehensive meta-analysis involving over 145,000 individuals from these groups led to the discovery of 41 significant genetic loci associated with kidney function, two of which hadn't been previously identified across any ancestry group.
- The study emphasizes the importance of diverse populations in genetic research for better understanding kidney disease and suggests that multi-ancestry polygenic scores can improve predictive capabilities and clinical applications.
Mitochondrial genomes can provide valuable information on the biology and evolutionary histories of their host organisms. Here, we present and characterize the complete coding regions of 107 mitochondrial genomes (mitogenomes) of cicadas (Insecta: Hemiptera: Auchenorrhyncha: Cicadoidea), representing 31 genera, 61 species, and 83 populations. We show that all cicada mitogenomes retain the organization and gene contents thought to be ancestral in insects, with some variability among cicada clades in the length of a region between the genes nad2 and cox1, which encodes 3 tRNAs.
View Article and Find Full Text PDFFor insects that depend on one or more bacterial endosymbionts for survival, it is critical that these bacteria are faithfully transmitted between insect generations. Cicadas harbor two essential bacterial endosymbionts, " Sulcia muelleri" and " Hodgkinia cicadicola." In some cicada species, has fragmented into multiple distinct but interdependent cellular and genomic lineages that can differ in abundance by more than two orders of magnitude.
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