Publications by authors named "Mariagrazia Irene Mineo"
Article Synopsis
- Cushing's syndrome, acromegaly, and neuroendocrine disorders lead to excess counterregulatory hormones, causing insulin resistance and requiring urgent treatment before surgery.
- The review highlights the importance of personalized medicine and patient-centered approaches in managing diabetes linked to these endocrine disorders.
- A practical therapeutic algorithm is proposed for managing diabetes in patients with conditions like glucagonoma, pheochromocytoma, Cushing's syndrome, and acromegaly, emphasizing the need for effective diabetes care in this patient group.
Objective: The aim of this study is to clarify, in girls with premature pubarche (PP), the influence of premature androgenization on the prevalence of polycystic ovary syndrome (PCOS).
Design And Patients: Ninety-nine PP girls, 63 who developed PCOS and 36 who did not develop PCOS, were retrospectively included. Clinical, anthropometric, and metabolic parameters were evaluated at the time of diagnosis of PP and after 10 years from menarche to find predictive factors of PCOS.
Background: The aim of the study was a retrospective comparison of the differences in maternal-foetal outcomes between women with type 1 and type 2 diabetes mellitus (T1DM and T2DM).
Methods: A cohort of 135 patients with pregestational diabetes, 73 with T1DM (mean age 29 ± 5 years) and 62 with T2DM (mean age 33 ± 6 years), in intensive insulin treatment throughout pregnancy were evaluated. Clinical and metabolic parameters and the prevalence of maternal and foetal complications were assessed.
Background: Conventional glucocorticoid treatment has a significant impact on liver in patients with adrenal insufficiency. Dual-release hydrocortisone (DR-HC) provides physiological cortisol exposure, leading to an improvement in anthropometric and metabolic parameters. We aimed to evaluate the effects of 12-month DR-HC treatment on the hepatic steatosis index (HSI), a validated surrogate index of hepatic steatosis, in patients with secondary adrenal insufficiency (SAI).
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