Validation of the Modified Determinant-Based Classification for Patients With Acute Pancreatitis in Intensive Care Medicine.

Objectives: To validate the Modified Determinant-Based Classification (MDBC) system, and compare it with the Revised Atlanta Classification (RAC) and the Determinant-Based Classification (DBC).

Methods: Prospective observational research was conducted in 35 international intensive care units, on patients with acute pancreatitis, and at least 1 organ failure (OF). Patient classification according to the MDBC was as follows: group 1 (transient OF, without local complications [LCs]), group 2 (transient OF and LC), group 3 (persistent OF, without LC), and group 4 (persistent OF and LC).

Development and validation of a multivariate prediction model for patients with acute pancreatitis in Intensive Care Medicine.

Background/objectives: Development and validation of a multivariate prediction model for patients with acute pancreatitis (AP) admitted in Intensive Care Units (ICU).

Methods: A prospective multicenter observational study, in 1 year period, in 46 international ICUs (EPAMI study).

Patients: adults admitted to an ICU with AP and at least one organ failure.

Comparison Between Revised Atlanta Classification and Determinant-Based Classification for Acute Pancreatitis in Intensive Care Medicine. Why Do Not Use a Modified Determinant-Based Classification?

Objective: To compare the classification performance of the Revised Atlanta Classification, the Determinant-Based Classification, and a new modified Determinant-Based Classification according to observed mortality and morbidity.

Design: A prospective multicenter observational study conducted in 1-year period.

Setting: Forty-six international ICUs (Epidemiology of Acute Pancreatitis in Intensive Care Medicine study).