Publications by authors named "Maria-Ioanna Gounaridi"
Hypertrophic cardiomyopathy (HCM) is a complex and heterogeneous cardiac disorder, often complicated by cardiogenic shock, a life-threatening condition marked by severe cardiac output failure. Managing cardiogenic shock in HCM patients presents unique challenges due to the distinct pathophysiology of the disease, which includes dynamic left ventricular outflow tract obstruction, diastolic dysfunction, and myocardial ischemia. This review discusses current and emerging therapeutic strategies tailored to address the complexities of HCM-associated cardiogenic shock and other diseases with similar pathophysiology that provoke left ventricular outflow tract obstruction.
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- - The study investigates how a 3-month cardiopulmonary rehabilitation program affects heart health and blood vessel stiffness in people recovering from COVID-19, comparing them to a non-COVID-19 group.
- - Results show significant improvements in arterial stiffness (PWV) and left ventricular function in the COVID-19 group who participated in rehabilitation, while these measures remained poor in those who didn't.
- - The findings suggest that rehabilitation effectively enhances recovery in heart-related metrics and overall physical fitness in post-COVID-19 patients, emphasizing the importance of such programs after the illness.
Article Synopsis
- Long COVID-19 syndrome is linked to cardiorespiratory issues, but its effect on exercise capacity is still unclear, leading researchers to study this relationship using cardiopulmonary exercise testing (CPET) and echocardiograms.
- The study involved 42 patients recovering from COVID-19 and 10 healthy participants, assessing heart function through various measures such as left ventricular ejection fraction (LVEF) and pulmonary artery pressure.
- Results showed that patients had significantly lower heart function and exercise capacity compared to healthy participants, with exercise intolerance being associated with left ventricular performance and pressures, indicating that heart health is crucial for recovery in long COVID-19.
Article Synopsis
- - The review analyzed the relationship between non-alcoholic fatty liver disease (NAFLD) and diastolic function of the left ventricle by searching published studies for echocardiographic parameters like E/e', left atrial volume index (LAVi), and left ventricular mass index (LVMi).
- - A total of 31 studies were included after an extensive search of 2619 articles, showing that NAFLD patients had a significantly higher prevalence of diastolic dysfunction (OR: 2.07) and increased E/e', LAVi, and LVMi levels compared to others.
- - The findings reinforce the idea that NAFLD is linked to heart issues, specifically heart failure
Coronavirus disease (COVID-19) is a respiratory disease, although arterial function involvement has been documented. We assess the impact of a post-acute COVID-19 rehabilitation program on endothelium-dependent vasodilation and arterial wall properties. We enrolled 60 convalescent patients from COVID-19 and one-month post-acute disease, who were randomized at a 1:1 ratio in a 3-month cardiopulmonary rehabilitation program (study group) or not (control group).
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- Significant improvements in treating coronary artery disease (CAD) have been made, emphasizing the importance of accurate diagnosis and management based on ischemia and viability evaluations.
- Non-invasive imaging techniques like stress echocardiography, CT coronary angiography, and cardiac MRI have enhanced the assessment of CAD, including the evaluation of plaque morphology.
- Advances in technologies like positron emission tomography (PET) and improved software for cardiac CT offer further insights, making it crucial to understand the strengths and limitations of each imaging method for effective treatment decisions.
Background: Coronavirus Disease-19 (COVID-19) is implicated in endotheliitis, which adversely affects cardiovascular events. The impact of vaccination with COVID-19 on the clinical outcome of patients is documented.
Objective: To evaluate the impact of vaccination with COVID-19 on the severe acute respiratory syndrome, coronavirus-2 (SARS-CoV-2) infection-related endothelial impairment.