Publications by authors named "Maria-Fatima Chilaca-Rosas"
Article Synopsis
- - The aneurysmal bone cyst is a benign bone tumor that creates blood-filled cavities and is relatively rare, making up about 1% of bone tumors globally.
- - This case discusses a pediatric patient with a cervical spine aneurysmal bone cyst, who experienced muscle pain and movement difficulties but improved under a multidisciplinary treatment approach involving surgery, embolization, radiation, and bisphosphonates.
- - The study highlights that a multidisciplinary strategy significantly enhanced the patient's quality of life and functionality, although further research is needed to establish standardized therapeutic protocols for such cases.
Identification of Radiomic Signatures in Brain MRI Sequences T1 and T2 That Differentiate Tumor Regions of Midline Gliomas with H3.3K27M Mutation.
Diagnostics (Basel)
August 2023
Background: Radiomics refers to the acquisition of traces of quantitative features that are usually non-perceptible to human vision and are obtained from different imaging techniques and subsequently transformed into high-dimensional data. Diffuse midline gliomas (DMG) represent approximately 20% of pediatric CNS tumors, with a median survival of less than one year after diagnosis. We aimed to identify which radiomics can discriminate DMG tumor regions (viable tumor and peritumoral edema) from equivalent midline normal tissue (EMNT) in patients with the positive H3.
View Article and Find Full Text PDFPurpose: Mexico and Central America have the highest childhood cancer incidence in the West. Pediatric-specific oncology knowledge contributes to the disparity. We sought to (1) determine the self-identified treatment patterns and needs of Mexican pediatric radiation oncologists and (2) pilot a workshop to improve contouring accuracy.
View Article and Find Full Text PDFArticle Synopsis
- Radiomics is a field that analyzes imaging data to extract high-dimensional features linked to biological events, particularly focusing on aggressive cancers like diffuse midline gliomas (DMG), which have a poor prognosis.
- In a study involving 91 DMG patients, 12 with the H3.3K27M mutation were examined using MRI data to extract radiomic features, involving various statistical methods to assess their significance.
- The analysis identified 13 significant radiomic features for predicting progression-free and overall survival, highlighting that certain texture profiles and features could assist in non-invasive diagnosis and assessment of DMG.
The application of Magnetic Resonance Imaging (MRI) have helped in different modalities for prostate cancer management, from early detection to treatment planning and follow-up, the evolution of MRI techniques allows to obtain not only anatomical but also functional information to take advantage of prostate cancer detection and staging while supplying prognostic and predictive biomarkers. This review presents conventional and advanced MRI techniques (known as multiparametric MRI) that allow functional and quantitative assessment of the normal prostate gland and its correlation with prostate cancer. Additional topics include the epidemiology of prostate cancer following the Global Burden Diseases Cancer Collaboration 2018, the clinical anatomy of the prostate gland, and the lower urinary tract; we also mention some aspects of the diagnosis performance in ultrasound.
View Article and Find Full Text PDFPurpose: To explore the response and toxicity of advanced non-metastatic squamous cell carcinomas of upper aerodigestive tract (SCC-UADT) to a combination of cetuximab concomitant with gemcitabine and radiotherapy.
Methods: We managed patients with concomitant treatment of cetuximab (400 mg/m(2) as uploading dose, then 250 mg/m(2), IV) concomitant with gemcitabine (50 mg/m(2)) weekly for seven courses, and radiotherapy in classical fractionation until completion of 70 Gy. Primary endpoints were complete response (CR) to treatment and toxicity.