Chemistry and properties of fluorescent pyrazole derivatives: an approach to bioimaging applications.

Fluorescent bioimaging is a crucial technique for studies in real cell samples, providing vital information about the metabolism of ions or molecules of biological and pharmaceutical significance. This technique typically uses probes based on organic small-molecule fluorophores, with N-heteroaromatic scaffolds playing an essential role due to their exceptional electronic properties and biocompatibility. Among these, pyrazole derivatives stand out as particularly promising due to their high synthetic versatility and structural diversity.

Chemosensors based on N-heterocyclic dyes: advances in sensing highly toxic ions such as CN and Hg.

CN and Hg ions are harmful to both the environment and human health, even at trace levels. Thus, alternative methods for their detection and quantification are highly desirable given that the traditional monitoring systems are expensive and require qualified personnel. Optical chemosensors (probes) have revolutionized the sensing of different species due to their high specificity and sensitivity, corresponding with their modular design.