Publications by authors named "Maria-Alessandra Damiano"
BCL2A1 is an anti-apoptotic member of the BCL-2 family that contributes to chemoresistance in a subset of tumors. BCL2A1 has a short half-life due to its constitutive processing by the ubiquitin-proteasome system. This constitutes a major tumor-suppressor mechanism regulating BCL2A1 function.
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- - The Brucella genus includes at least 10 closely related species that affect various hosts, including humans, and the new species Brucella microti has a unique GAD system that helps it survive acidic conditions and infect mice.
- - A study on 47 Brucella isolates revealed that while the classical species lack a functional GAD system, certain marine and newly identified species do possess it, making them more resistant to acid environments.
- - The GAD system's function could be key for these atypical Brucella species adapting to acidic environments, and it may also serve as a diagnostic tool to differentiate them from other Brucella and Ochrobactrum strains.
Profiling the physiological and molecular response to sulfonamidic drug in Procambarus clarkii.
Comp Biochem Physiol C Toxicol Pharmacol
November 2014
Sulfamethoxazole (SMZ) is one of the most widely employed sulfonamides. Because of the widespread use of SMZ, a considerable amount is indeed expected to be introduced into the environment. The cytotoxicity of SMZ relies mainly on arylhydroxylamine metabolites (S-NOH) of SMZ and it is associated with the production of reactive oxygen species (ROS).
View Article and Find Full Text PDFThis study examined the effects of an acoustic stimulus on the haemolymph and agonistic behaviour of the red swamp crayfish, Procambarus clarkii. The experiment was conducted in a tank equipped with a video recording system using six groups (three control and three test groups) of five adult crayfish (30 specimens in total). After 1 h of habituation, the behaviour of the crayfish was monitored for 2 h.
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