Publications by authors named "Maria-Alejandra Meneses-Toro"
Objective: The objective is to describe the HLA allelic frequency in PsA and correlate it with demographic and clinical variables.
Methods: Retrospective study of adult patients with a diagnosis of PsA (n=23) and healthy controls (n=46), all with a request for HLA-A, B, C, DR. Typing was performed using HLA-PCR/SSO LifeCodes and analyzed on the LUMINEX IS100/200 xMAP system.
Objective: This study aimed to establish the association between HLA-A, B, DR genotypes and gastrointestinal variables in patients with SpA without inflammatory bowel disease (IBD).
Methods: Retrospective study of 91 patients with SpA and 401 healthy controls, with typing by Illumina Sequencing/PacBio and LIFECODES HLA-PCR/SSO multiplex sequencing technology. The presence of gastrointestinal symptoms was evaluated by administering a survey, and those who presented 2 or more symptoms were taken for clinical evaluation by rheumatology and gastroenterology, colonoscopy and histopathological study.
Low Frequency of Upper Gastrointestinal Bleeding Despite Non-Steroidal Anti-Inflammatory Drugs and Corticosteroids in Patients with Rheumatoid Arthritis.
Curr Rheumatol Rev
July 2024
Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease. It has been identified that non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids can be essential risk factors for developing complications such as upper gastrointestinal bleeding (UGIB).
Objective: This study aimed to describe the safety profile of drugs used to treat RA focused in UGIB.
Article Synopsis
- Psoriatic arthritis (PsA) is a complex inflammatory condition influenced by posttranslational modifications, which can affect various biological processes and disease outcomes.
- A systematic review of 587 articles led to the inclusion of 47 relevant studies focused on identifying specific posttranslational modifications in PsA, such as citrullination and phosphorylation, and their relationship with disease progression.
- The findings suggest that certain modifications, like citrullination and glycosylation, are linked to worse disease outcomes and may serve as potential biomarkers for diagnosis and treatment strategies in PsA.
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an uncommon subtype of peripheral neuropathy, especially in systemic lupus erythematosus (SLE). We report a case of SLE presenting with CIDP successfully treated. The patient presented with bilateral, progressive, ascending, sensory, and motor neuropathy.
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