Publications by authors named "Maria do Carmo Lacerda Barbosa"

Açaí, Mart., is a native plant from the Amazonian and is rich in several phytochemicals with anti-tumor activities. The aim was to analyze the effects of açaí seed oil on colorectal adenocarcinoma (ADC) cells.

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Background: HPV is strongly related to cervical cancer. HPV lineages can contribute to a response to cervical cancer therapy. The aim of this research was to estimate the frequency of human papillomavirus (HPV)-16 lineages in specimens of cervical cancer, relate the pathological factors in these variants, and assess their response to treatment with radical chemoradiotherapy.

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Problem Of Research: Candida spp. biofilms are complex microbial communities that have been associated with increasing resistance to clinically available antifungal drugs. Hence, novel pharmacological approaches with ability to inhibit biofilm formation have been investigated.

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Açaí ( Mart) is an Amazon plant with many biological properties. Previous report of this group evidenced autophagy induction after treatment with açaí seed extract in MCF-7 breast cancer cell lines by acridine orange assay. The aim of this study was to evaluate the ultrastructural changes induced by açaí seed extract in MCF-7 breast cancer cell lines.

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Background: Zika virus (ZIKV) is a flavivirus associated with microcephaly and other fetal anormalities. However, evidence of asymptomatic ZIKV infection in pregnant women is still scarce. This study investigated the prevalence of Zika infection in asymptomatic pregnant women attending two public maternities in Maranhão state, Northeast Brazil.

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Background: Cardiovascular disease (CVD) is the leading cause of death in Western civilizations. The type of fatty acid which makes up the diet is related to the cardiovascular morbimortality and the formation of atheromas. Populations with high consumption of oils and fats have a higher number of deaths from CVD.

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Article Synopsis
  • - Cervical cancer is a major health issue for women globally, particularly in Brazil where it's the third most common cancer, with HPV found in around 90% of cases, predominantly HPV 16 variants contributing to its development.
  • - A study analyzed tumor samples from 120 cervical cancer patients, revealing that HPV was present in 73% of cases, with HPV 16 being the most common type, especially variant A, which was linked to specific tumor histological types.
  • - Understanding the variants of HPV 16 is crucial as it helps clarify their role in the progression and characteristics of cervical cancer, potentially impacting future research and treatment strategies.
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Background: Flavonoids from a variety of fruits, including açaí, have beneficial antioxidant activity in several diseases, including cancer. Breast cancer is the second most prevalent cancer among Brazilian women. Studies have shown the action of flavonoids on neoplastic cells, as well as on diabetes and neurodegenerative and cardiovascular diseases.

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Article Synopsis
  • Human papillomavirus (HPV) infection varies by region and is prevalent in Quilombo communities in Brazil, which face unique health access challenges.
  • The study focused on 395 Quilombola women to identify specific HPV types and their association with sociodemographic factors and cervical abnormalities.
  • Results showed a 12.6% HPV infection rate, with high-risk types predominant; a significant link was found between HPV presence and cytological abnormalities, particularly in younger women.
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Introduction: Climacteric women are susceptible to a number of changes, among them osteoporosis. Osteoporosis is a disease characterized by low bone mass and susceptibility to fracture. Currently, this disease is a public health issue, being necessary to recognize its risk factors.

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A cross-sectional population-based study using questionnaire and anthropometric data was conducted on 968 university students of São Luís, Brazil, from which 590 showed up for blood collection. In the statistical analysis the Student t-test, Mann-Whitney and chi-square tests were used. The prevalence of metabolic syndrome by the Joint Interim Statement (JIS) criteria was 20.

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