Background: Fluconazole-resistant Candida parapsilosis (FRCP) is a matter of concern in Spain.
Objectives: We here report a FRCP spread across a 777-bed referral hospital located in Burgos, Spain, during the COVID-19 pandemic.
Patients/methods: In April 2021, an FRCP isolate (MIC = 64 mg/L, E-test®) from a hospitalised patient was detected.