Prediction of the rate of decline in fetal hemoglobin levels between first and second transfusions in red cell alloimmune disease.

Objective: To determine variables that predict the rate of decline in fetal hemoglobin levels in alloimmune disease.

Method: Retrospective review of singleton pregnancies that underwent first and second intrauterine transfusions for treatment of fetal anemia because of maternal Rh alloimmunization in a tertiary referral center.

Results: Forty-one first intrauterine transfusions were performed at 26.