Publications by authors named "Maria de Los Reyes Pascual-Perez"
Background: Patients with chronic lung disease (CLD), such as asthma or chronic obstructive pulmonary disease, were expected to have an increased risk of clinical manifestations and severity of COVID-19. However, these comorbidities have been reported less frequently than expected. Chronic treatment with inhaled corticosteroids (ICS) may impact the clinical course of COVID-19.
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- - The study investigates the relationship between COVID-19 and heart failure (HF), focusing on identifying risk factors for HF among hospitalized COVID-19 patients in Spain.
- - A total of 16,474 patients were analyzed, with 5.8% developing HF; significant risk factors included older age, atrial fibrillation, obesity, and peripheral vascular disease.
- - Patients who developed HF had notably higher mortality rates, increased need for intubation, and higher ICU admission rates compared to those who did not develop HF.
Article Synopsis
- * A study involving over 14,000 patients revealed that smokers were generally older, predominantly male, and had more underlying health issues, which contributed to their increased risk.
- * The research indicates that both current and former smokers are at a greater risk for complications after being hospitalized for COVID-19, highlighting smoking as a significant factor in disease severity.
Background: The WHO ordinal severity scale has been used to predict mortality and guide trials in COVID-19. However, it has its limitations.
Objective: The present study aims to compare three classificatory and predictive models: the WHO ordinal severity scale, the model based on inflammation grades, and the hybrid model.
Article Synopsis
- Smoking is linked to more severe outcomes in COVID-19 patients, showing increased rates of ICU admissions and in-hospital mortality compared to non-smokers.
- A study of over 14,000 COVID-19 patients in Spain found that smokers were older, predominantly male, and had worse health profiles.
- The research suggests that both current and former smokers face a higher risk of complications from COVID-19, indicating that smoking is a significant factor in determining patient prognosis.
We aimed to determine the impact of steroid use in COVID-19 in-hospital mortality, in a retrospective cohort study of the SEMICOVID19 database of admitted patients with SARS-CoV-2 laboratory-confirmed pneumonia from 131 Spanish hospitals. Patients treated with corticosteroids were compared to patients not treated with corticosteroids; and adjusted using a propensity-score for steroid treatment. From March-July 2020, 5.
View Article and Find Full Text PDFThere is some evidence that male gender could have a negative impact on the prognosis and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of the present study was to compare the characteristics of coronavirus disease 2019 (COVID-19) between hospitalized men and women with confirmed SARS-CoV-2 infection. This multicenter, retrospective, observational study is based on the SEMI-COVID-19 Registry.
View Article and Find Full Text PDFBackground: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with COVID-19 and identify risk factors for in-hospital mortality at admission.
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