Clinical Considerations Derived From the Administration of Melatonin to Children With Sleep Disorders.

Background And Objectives: Despite the numerous investigations carried out in relation to melatonin, there is a lack of knowledge about the specific melatonin secretion patterns in the diverse primary sleep disturbances. The objective of this study was to analyze the plasma melatonin concentrations in children with primary sleep disorders and the effects of melatonin therapy on their serum levels and their actigraphic sleep parameters.

Methods: Fourteen participants (nine girls; seven to 14 years old) diagnosed with diverse primary sleep disorders were recruited.