Hematological Alterations in Patients Recovered from SARS-CoV-2 Infection in Havana, Cuba.

Introduction: COVID-19 sequelae, or the short-, medium-, and long-term manifestations of the disease are under continuous study. There are currently few reports on the evolution of hematological variables following a demonstrated absence of SARS-CoV-2 after infection.

Objective: Identify hematological alterations in Cuban adults recovered from SARS-CoV-2 infection, and their relation with disease severity.

The role of tumor necrosis factor alpha - 308A > G polymorphism on the clinical states of SARS-CoV-2 infection.

Background: Tumor necrosis factor-alpha (TNFɑ) is a cytokine that manages the host defense mechanism, which may play a role in the pathogenesis of COVID-19 patients. Several single-nucleotide polymorphisms, described in the promoter region of the TNFα gene, have a significant role on its transcriptional activity. These include the - 308A > G polymorphism which increases the TNFα levels with the expression of the A allele.

TaqI polymorphism of the VDR gene: aspects related to the clinical behavior of COVID-19 in Cuban patients.

Purpose: To determine the relationship between the genotypes of the TaqI polymorphism of gene and the clinical forms of COVID-19 in Cuban patients.

Methods: TaqI polymorphism was determined by the PCR in 104 Cuban patients, who suffered different clinical forms of COVID-19.

Results: There was a greater possibility of presenting symptomatic forms [OR = 2.