Distal intestinal obstruction syndrome: a diagnostic and therapeutic challenge in cystic fibrosis.

Objective: To evaluate the demographics, genotype, and clinical presentation of pediatric patients presenting with distal intestinal obstruction syndrome (DIOS), and factors associated with DIOS recurrence.

Methods: Case series of ten patients (median age 13.2 years), followed-up in a reference center, retrospectively assessed.

Lung disease and vitamin D levels in cystic fibrosis infants and preschoolers.

Introduction: Vitamin D acts on the immune system and lung response. Patients with cystic fibrosis (CF) may be deficient in this vitamin. The aims of the study were to evaluate vitamin D levels and severity of lung disease in infants and preschoolers diagnosed with CF, and to compare them to a group of children without pancreatic insufficiency (PI).