Evaluation of SiO2 sonogels, prepared by a new catalyst-free method, as drug delivery system.

Recently, we reported on the synthesis of catalyst-free SiO(2) sonogels prepared by the sonication of a neutral distilled water/ tetraethyl ortosilicate mixture. The purpose of the present study was to evaluate the feasibility of using these sonogels as pharmaceutical delivery systems. A certified color additive (sunset yellow, SY) was used as a model compound for the release experiments.