Publications by authors named "Maria Y Munoz-Paredes"
Br J Clin Pharmacol
March 2024
Article Synopsis
- The study aimed to analyze how genetic variations in the VKORC1 and CYP2C9 genes affect warfarin maintenance doses in Peruvian patients on anticoagulation therapy.
- Conducted in a hospital in Lima, the research included 70 outpatients who had stable warfarin doses and appropriate blood clotting levels, with DNA samples collected for genetic analysis.
- Results showed that patients with the AA genotype of the VKORC1 gene needed a significantly lower average dose of warfarin compared to those with the GA and GG genotypes, while no notable association was found with the CYP2C9 gene.
