Bidirectional relationships between chronotype and sleep hygiene in children with and without parental history of alcohol use disorder.

Study Objectives: Children with evening chronotype may be at risk for insufficient sleep because their chronotype makes it difficult to sustain healthy sleep habits. We evaluated bidirectional relationships between chronotype and sleep hygiene.

Methods: Two hundred forty-six children (n = 246 at T1, n = 200 at T2, n = 147 at T3), with a mean age of 9.

The Mediating Role of Sleep Quality, Regularity, and Insomnia on the Relationship Between Adverse Childhood Experiences and Resilience.

Adverse childhood experiences (ACEs) have been linked to many negative outcomes in prior psychological literature. Previous studies have shown that ACEs are related to sleep problems (e.g.

The mutagenic forces shaping the genomic landscape of lung cancer in never smokers.

Lung cancer in never smokers (LCINS) accounts for up to 25% of all lung cancers and has been associated with exposure to secondhand tobacco smoke and air pollution in observational studies. Here, we evaluate the mutagenic exposures in LCINS by examining deep whole-genome sequencing data from a large international cohort of 871 treatment-naïve LCINS recruited from 28 geographical locations within the Sherlock- study. mutations were 3.

The Dual Role of the NFATc2/galectin-9 Axis in Modulating Tumor-Initiating Cell Phenotypes and Immune Suppression in Lung Adenocarcinoma.

Tumor-initiating cells (TICs) resilience and an immunosuppressive microenvironment are aggressive oncogenic phenotypes that contribute to unsatisfactory long-term outcomes in lung adenocarcinoma (LUAD) patients. The molecular mechanisms mediating the interaction between TICs and immune tolerance have not been elucidated. The role of Galectin-9 in oncogenesis and immunosuppressive microenvironment is still unknown.

Attachment relationship quality with mothers and fathers and child temperament: An individual participant data meta-analysis.

A growing body of research suggests that, compared with single parent-child attachment relationships, child developmental outcomes may be better understood by examining the configurations of child-mother and child-father attachment relationships (i.e., attachment networks).

Configurations of mother-child and father-child attachment relationships as predictors of child language competence: An individual participant data meta-analysis.

An individual participant data meta-analysis was conducted to test pre-registered hypotheses about how the configuration of attachment relationships to mothers and fathers predicts children's language competence. Data from seven studies (published between 1985 and 2014) including 719 children (M : 19.84 months; 51% female; 87% White) were included in the linear mixed effects analyses.

Predicting the stalking of celebrities from measures of persistent pursuit and threat directed toward celebrities, sensation seeking and celebrity worship.

The stalking of celebrities is a serious issue for thousands of celebrities worldwide who are occasionally confronted by fans who merit the label "fanatic." We administered measures of obnoxious celebrity stalking, celebrity worship, persistent pursuit of celebrities, threat directed toward celebrities, boredom susceptibility, disinhibition, experience seeking, thrill and adventure seeking, relationship styles, and anger to 596 college students from the U.S.

Targeting GSTP1 as Therapeutic Strategy against Lung Adenocarcinoma Stemness and Resistance to Tyrosine Kinase Inhibitors.

Glutathione S-transferase pi (GSTP1), a phase II detoxification enzyme, is known to be overexpressed and mediates chemotherapeutic resistance in lung cancer. However, whether GSTP1 supports cancer stem cells (CSCs) and the underlying mechanisms in lung adenocarcinoma (LUAD) remain largely unknown. This study unveiled that GSTP1 is upregulated in lung CSCs and supports tumor self-renewal, metastasis, and resistance to targeted tyrosine kinase inhibitors of LUAD both in vitro and in vivo.

Convergence Between the Child Behavior Checklist Sleep Items, Actigraphy and Other Sleep Measures Among Children of Parents with Alcoholic Disorders and Controls.

Purpose: The Child Behavior Checklist (CBCL) is a widely used instrument of children psychosocial functioning. CBCL sleep items have been used in both clinical settings and research. To date, few empirical studies have examined the relationships between CBCL sleep items and other sleep measures such as actigraphy and validated sleep questionnaires.

Conceptual comparison of constructs as first step in data harmonization: Parental sensitivity, child temperament, and social support as illustrations.

This article presents a strategy for the initial step of data harmonization in Individual Participant Data syntheses, i.e., making decisions as to which measures operationalize the constructs of interest - and which do not.

Reducing chilling injury in 'Palmer' mangoes submitted to quarantine cold treatment.

Background: Treatment with low temperatures can be used to quarantine mangoes against fruit-fly infestation. However, mangoes can develop chilling injury (CI) when stored at temperatures below 13 °C. We demonstrated that the immersion in polyol solutions can alleviate CI symptoms in 'Palmer' mangoes stored at 8 °C.

Configurations of mother-child and father-child attachment as predictors of internalizing and externalizing behavioral problems: An individual participant data (IPD) meta-analysis.

An unsettled question in attachment theory and research is the extent to which children's attachment patterns with mothers and fathers jointly predict developmental outcomes. In this study, we used individual participant data (IPD) meta-analysis to assess whether early attachment networks with mothers and fathers are associated with children's internalizing and externalizing behavioral problems. Following a pre-registered protocol, data from 9 studies and 1,097 children (mean age: 28.

Modified Ponseti Technique in an Eleven-Year-Old with Bilateral Untreated Clubfoot: A Case Report.

We report the case of an eleven-year-old girl with untreated bilateral clubfoot. She had a total of nine long leg castings changed weekly, Achilles tendon Z-lengthening and posterior ankle release followed by another six weeks of long leg cast immobilization post-operatively. We encouraged using night-time foot abduction brace for twelve months.

Population Dynamics and Tree Damage of the Invasive Chestnut Gall Wasp, , in Its Southernmost European Distributional Range.

The invasive chestnut gall wasp (CGW), , the worst pest of chestnut cultivation, has spread worryingly throughout Europe in less than 20 years. Despite the great concern around this pest, little is known about the status in its southernmost distribution in continental Europe. We assessed spatio-temporal patterns in the population dynamics, phenology and tree damage caused by CGW in southern Spain.

Influence of Pre-Harvest Bagging on the Incidence of Newstead (Hemiptera: Diaspididae) and Fruit Quality in Mango.

Newstead (Hemiptera: Diaspididae) is the main pest of mango, L., in Spain, causing significant economic losses by aesthetic damage that reduce the commercial value of fruit. Bagging fruit with two commercial bags (a yellow satin paper and a white muslin cloth bag) was evaluated for control of in two organic mango orchards during the 2020 cropping season in pursuit of the development of a mango IPM program to produce pest-free and residue-free fruits.

Delay discounting and obesity in food insecure and food secure women.

Objectives: The relation between food insecurity (FI) and delay discounting (DD) and probability discounting (PD) for food and money was tested in women. In addition, discounting was tested as a variable that mediates the relation between obesity and FI.

Method: Women recruited from a community sample (N = 92) completed questionnaires.

Nidogen 1-Enriched Extracellular Vesicles Facilitate Extrahepatic Metastasis of Liver Cancer by Activating Pulmonary Fibroblasts to Secrete Tumor Necrosis Factor Receptor 1.

In hepatocellular carcinoma (HCC) patients with extrahepatic metastasis, the lung is the most frequent site of metastasis. However, how the lung microenvironment favors disseminated cells remains unclear. Here, it is found that nidogen 1 (NID1) in metastatic HCC cell-derived extracellular vesicles (EVs) promotes pre-metastatic niche formation in the lung by enhancing angiogenesis and pulmonary endothelial permeability to facilitate colonization of tumor cells and extrahepatic metastasis.

The latent structure of the adult attachment interview: Large sample evidence from the collaboration on attachment transmission synthesis.

The Adult Attachment Interview (AAI) is a widely used measure in developmental science that assesses adults' current states of mind regarding early attachment-related experiences with their primary caregivers. The standard system for coding the AAI recommends classifying individuals categorically as having an autonomous, dismissing, preoccupied, or unresolved attachment state of mind. However, previous factor and taxometric analyses suggest that: (a) adults' attachment states of mind are captured by two weakly correlated factors reflecting adults' dismissing and preoccupied states of mind and (b) individual differences on these factors are continuously rather than categorically distributed.