Autologous skin fibroblast and keratinocyte grafts in the treatment of chronic foot ulcers in aging type 2 diabetic patients.

Background: we assessed the tolerability and efficacy of autologous skin cell grafts in older type 2 diabetic patients with chronic foot ulcers.

Methods: treatment with Hyalograft 3D and Laserskin Autograft was proposed to a consecutive series of type 2 diabetic patients older than 65 years affected by long-standing (>6 months) foot ulcers with an area greater than 15 cm(2). Ulcer healing rates and measurements of ulcer area were determined monthly for 12 months.

Pulse pressure and prediction of incident foot ulcers in type 2 diabetes.

Objective: To assess the relevance of pulse pressure as a predictor of foot ulcers in type 2 diabetic subjects.

Research Design And Methods: A cohort study was performed on a consecutive series of 1,945 type 2 diabetic outpatients without a foot ulcer at baseline. Incident foot ulcers were identified through the regional hospital discharge system, which contains ICD codes of current diagnoses.