Publications by authors named "Maria Victoria Branco Flores"
Regul Toxicol Pharmacol
June 2019
Article Synopsis
- Manganese (Mn) is essential for biological functions but becomes toxic when accumulated excessively, particularly impacting the central nervous system (CNS), with limited research on its effects in other tissues.
- This study examined how Mn exposure affects oxidative stress, metabolism, and Mn levels in peripheral organs of male and female Wistar rats, using various doses over a month-long period.
- The findings indicated that while Mn concentrations increased in organs (especially kidneys), there were significant sex-related differences in toxic effects, with males showing greater oxidative stress and altered metabolic responses compared to females, despite similar levels of Mn deposition.
