Liver injury after SARS-CoV-2 vaccination: Features of immune-mediated hepatitis, role of corticosteroid therapy and outcome.

Background And Aims: A few case reports of autoimmune hepatitis-like liver injury have been reported after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. We evaluated clinical features, treatment response and outcomes of liver injury following SARS-CoV-2 vaccination in a large case series.

Approach And Results: We collected data from cases in 18 countries.

Prospective Latin American cohort evaluating outcomes of patients with COVID-19 and abnormal liver tests on admission.

Introduction & Objectives: The independent effect of liver biochemistries as a prognostic factor in patients with COVID-19 has not been completely addressed. We aimed to evaluate the prognostic value of abnormal liver tests on admission of hospitalized patients with COVID-19.

Materials & Methods: We performed a prospective cohort study including 1611 hospitalized patients with confirmed SARS-CoV-2 infection from April 15, 2020 through July 31, 2020 in 38 different Hospitals from 11 Latin American countries.

[Hepatic glycogenosis: a case report].

The glycogen storage diseases contain a range of diseases that are characterized by the abnormal storage or utilization of glycogen, the organs most affected being muscle and / or liver. Hepatomegaly may be a clinical sign that could guide to the diagnosis. We describe a 15-year-old patient with hepatomegaly, hypertransaminasemia and growth retardation.

Droplets deposition pattern from a prototype of a fixed spraying system in a sloping vineyard.

In Italy high-quality vines are sometimes grown in small fields with slope steeper than 5-10%, where an air-blast sprayer is impractical so spray-gun application of pesticides is used, a technique that is very costly and labour intensive, and that causes high pesticide exposure of the operators. A possible alternative is the use of a fixed spraying system, and the first researches are in progress in Italy. A fixed spraying system prototype was built in a vineyard at Laimburg Research Centre with an upper line with micro-sprinkler and a lower line with cooler-type nozzles, and a trial was performed with the aim of measuring the deposition pattern of droplets on the row and between rows with water sensitive papers, also in comparison with a precise low-drift air-blast sprayer.