Publications by authors named "Maria V Altavilla"
Article Synopsis
- Transorbital neuroendoscopic surgery (TONES) includes techniques for treating spheno-orbital tumors, showing promising results in patient outcomes based on a clinical series and literature review.
- In a study involving 22 patients, gross tumor removal was achieved in 36.4% with the eTOA alone, and 50% with a combination method, with the most common tumor type being meningioma.
- The eTOA demonstrated advantages like improved patient recovery, minimal complications, and good cosmetic results, but it requires advanced surgical skills and should be performed in specialized centers.
PRAME (PReferentially expressed Antigen in MElanoma), a cancer-testis antigen expressed in normal and neoplastic tissues with several functions, proved to be a useful diagnostic tool in the differential diagnosis between benign and malignant melanocytic lesions. The current study aims to perform PRAME stain on a retrospective case series of mucosal melanocytic tumors of the head and neck region to compare 3 different scores and evaluate the most reliable one in this diagnostic set. Immunohistochemical analysis for PRAME was performed in 54 benign and malignant mucosal melanocytic tumors of the head and neck region collected from 41 patients.
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