Publications by authors named "Maria Urbana Pinto Brandao Rondon"
High-dose Chemotherapy Impairs Cardiac Autonomic Control of Hospitalized Cancer Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation.
Clin Lymphoma Myeloma Leuk
March 2023
Article Synopsis
- Autologous hematopoietic stem cell transplantation (HSCT) patients experience deteriorating cardiac autonomic control during their hospital stay, particularly after high-dose chemotherapy, which is linked to increased mortality risks.
- A study compared cardiac autonomic control in HSCT patients with cancer-free outpatients and found significant declines in various cardiac metrics during hospitalization, especially at discharge.
- Results indicated that impaired cardiac autonomic control in HSCT patients correlates with early signs of cardiotoxicity, highlighting the need for monitoring cardiac health during treatment.
Exercise training (ET) can lower platelet reactivity in patients with cardiovascular risk factors. However, the effects of ET on platelet reactivity in higher-risk patients is unknown. The aim of this study was to evaluate the effects of ET on platelet reactivity in patients with recent myocardial infarction (MI).
View Article and Find Full Text PDFInspiratory muscle training in addition to conventional physical rehabilitation in hospitalized patients undergoing hematopoietic stem cell transplantation: a randomized controlled trial.
Support Care Cancer
November 2022
Purpose: To investigate the effect of inspiratory muscle training (IMT) in addition to conventional physical rehabilitation on muscle strength, functional capacity, mobility, hemodynamics, fatigue, and quality of life in hospitalized patients undergoing hematopoietic stem cell transplantation (HSCT).
Methods: We conducted a randomized controlled trial in 57 inpatients with hematological diseases undergoing HSCT. Conventional inpatient physical rehabilitation was delivered to the IMT (n = 27) and control (CON; n = 30) groups according to usual care, and the first group additionally performed IMT.
Alpha2A-adrenergic receptor and eNOS genetic polymorphisms are associated with exercise muscle vasodilatation in apparently healthy individuals.
Int J Cardiol Heart Vasc
December 2016
Purpose: Muscle vasodilatation during exercise has been associated with cardiovascular health and may be influenced by genetic variability. The purpose of this study was to evaluate functional genetic polymorphisms of physiologic pathways related to the regulation of the cardiovascular function (alpha-adrenergic receptors, endothelial nitric oxide synthase and bradykinin B receptor) and exercise muscle vasodilatation in apparently healthy men and women.
Methods: We enrolled 689 individuals without established cardiovascular disease that had attended a check-up program.
Purpose: The neurovascular mechanisms underlying hypertension are minimized by exercise training. However, it is not known whether previously trained individuals with hypertension would have deleterious repercussion of this disease. Our aim was to investigate the neurovascular control and the cardiac structure of athletes with hypertension.
View Article and Find Full Text PDFExercise-induced muscle vasodilatation and treadmill exercise test responses in individuals without overt heart disease.
Cardiology
August 2014
Article Synopsis
- The study investigated how exercise affects cardiovascular health, focusing on the relationship between heart responses during a treadmill test and muscle vasodilation in people without heart disease.
- It involved 796 asymptomatic participants, measuring heart rate, blood pressure, and muscle blood flow during exercise.
- Results showed that better muscle blood flow during exercise was linked to improved heart rate recovery and lower diastolic blood pressure, but exercise capacity did not correlate with muscle vasodilation.
Background: Brazil is the world's largest producer of sugarcane. Harvest is predominantly manual, exposing workers to health risks: intense physical exertion, heat, pollutants from sugarcane burning.
Design: Panel study to evaluate the effects of burnt sugarcane harvesting on blood markers and on cardiovascular system.
Purpose: Previous studies showed that anabolic androgenic steroids (AAS) increase vascular resistance and blood pressure (BP) in humans. In this study, we tested the hypotheses 1) that AAS users would have increased muscle sympathetic nerve activity (MSNA) and reduced forearm blood flow (FBF) compared with AAS nonusers and 2) that there would be an association between MSNA and 24-h BP.
Methods: Twelve AAS users aged 31 +/- 2 yr (means +/- SE) and nine age-matched AAS nonusers aged 29 +/- 2 yr participated in the study.
Background: Sympathetic hyperactivity is one of the mechanisms involved in the increased cardiovascular risk associated with depression, and there is evidence that antidepressants decrease sympathetic activity.
Objectives: We tested the following two hypotheses: patients with major depressive disorder with high scores of depressive symptoms (HMDD) have augmented muscle sympathetic nervous system activity (MSNA) at rest and during mental stress compared with patients with major depressive disorder with low scores of depressive symptoms (LMDD) and controls; sertraline decreases MSNA in depressed patients.
Methods: Ten HMDD, nine LMDD and 11 body weight-matched controls were studied.