Publications by authors named "Maria Teresa Pesce"

Background: The increasing incidence, rapidly evolving classification, rarity and heterogeneity of neuroendocrine neoplasms (NENs) pose challenges to NEN registration including difficulty in distinguishing neuroendocrine carcinoma (NEC) and neuroendocrine tumours (NETs). Thus, in Italy a higher NEC incidence was reported. Focusing on gastroenteropancreatic (GEP) NEN, we aimed to review GEP NEN, and in particular cases of neuroendocrine carcinoma, not otherwise specified (NOS) and estimate the incidence of NEN, NET and NEC of the GEP.

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Article Synopsis
  • The study evaluates cancer incidence trends from 2008-2017 in Italy among individuals aged 20-49, utilizing data from 20 cancer registries that cover about one-third of the population.
  • Results show that cancer rates were nearly double for women compared to men, particularly due to breast and thyroid cancers, with significant variations in incidence trends across different cancer types.
  • The findings indicate no consistent increase for early-onset cancers in Italy, with rising rates for some cancers offset by declines in others, underscoring the need for preventive measures and careful screening strategies.
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  • Five-year survival rates for vulvar squamous cell carcinoma (VSCC) patients in Italy haven't improved over the past 30 years, which raises concerns about treatment effectiveness.
  • A study of cancer registries found that in 2018, about 6,620 women in Italy were living with VSCC, but only 32% of newly diagnosed patients are considered curable, with many facing high mortality rates even after five years.
  • The results highlight a critical need to revamp the vulvar care approach in Italy to better address the ongoing challenges in managing VSCC.
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People alive many years after breast (BC) or colorectal cancer (CRC) diagnoses are increasing. This paper aimed to estimate the indicators of cancer cure and complete prevalence for Italian patients with BC and CRC by stage and age. A total of 31 Italian Cancer Registries (47% of the population) data until 2017 were included.

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Objectives: To describe the procedures to derive complete prevalence and several indicators of cancer cure from population-based cancer registries.

Materials And Methods: Cancer registry data (47% of the Italian population) were used to calculate limited duration prevalence for 62 cancer types by sex and registry. The incidence and survival models, needed to calculate the completeness index () and complete prevalence, were evaluated by likelihood ratio tests and by visual comparison.

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Purpose: The aim of this study was to compare the functional characteristics of two computer-based systems for quality control of cancer registry data through analysis of their output differences.

Methods: The study used cancer incidence data from 22 of the 49 registries of the Italian Network of Cancer Registries registered between 1986 and 2017. Two different data checking systems developed by the WHO International Agency for Research on Cancer (IARC) and the Joint Research Center (JRC) with the European Network of Cancer Registries (ENCR) and routinely used by registrars were used to check the quality of the data.

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