miRNome Profiling of Extracellular Vesicles in Patients With Severe COVID-19 and Identification of Predictors of Mortality.

Background: Extracellular vesicles (EVs), containing microRNAs (miRNAs) and other molecules, play a central role in intercellular communication, especially in viral infections caused by SARS-CoV-2. This study explores the miRNA profiles in plasma-derived EVs from patients with severe COVID-19 vs controls, identifying potential mortality predictors.

Methods: This prospective study included 36 patients with severe COVID-19 and 33 controls without COVID-19.

Bilateral fungal infection inducing a serpiginous-like picture.

Purpose: To report the clinical findings of a patient who presented with an atypical bilateral fungal retinitis that was established by retinochoroidal biopsy.

Methods: Case report.

Results: A 56-year-old systemically healthy man presented with progressive visual loss in his left eye for 3 weeks.

Impact of ventilator-associated pneumonia on mortality and epidemiological features of patients with secondary peritonitis.

Background: Despite the significant impact of nosocomial infections on the morbidity and mortality of patients staying in the intensive care unit (ICU), no study over the past 20 years has focused specifically on VAP following secondary peritonitis. The objective of the present study was to determine in-hospital mortality and epidemiological features attributed to ventilator-associated pneumonia (VAP) following secondary peritonitis.

Methods: Prospective observational study involved 418 consecutive patients admitted in the ICU.