Introduction: Due to globalization and migratory movements, HBeAg+ chronic hepatitis B is becoming increasingly important in Spain.
Objective: To analyze the epidemiological features, progression, and treatment response to oral antiviral agents (OA) in HBeAg+ chronic hepatitis B patients in our area.
Material And Methods: We analyzed 436 patients with chronic hepatitis B infection followed up at the Ramón y Cajal Hospital from 1990 to June 2012.