Effects of environmental contaminents, such as air pollution and cigarette smoking on skin include increased oxidation, subclinical inflammation, and degradation of the dermal matrix, which can accelerate the skin aging process. An open-label, prospective study was conducted to assess the efficacy and tolerability of a topical anti-aging regimen comprising high-concentration retinoids, extract, and niacinamide in participants living in a heavily polluted (Level III, World Health Organization) city. Twenty-two female Caucasian volunteers with Fitzpatrick Skin Types III and IV were treated for 90 days with the topical anti-aging regimen.
View Article and Find Full Text PDFIntroduction: Cutaneous regeneration, fractional laser, medical device, cellular proliferation cutaneous changes linked to photoaging are currently treated with physical treatments, such as fractional laser, which may induce epidermal alteration.
Objective: To determine the efficacy and safety of a regenerative serum (Matricium , Laboratoire Bioderma, France) after laser procedure.
Methods: Prospective, double-blind, controlled, and randomized study in subjects with photoaged skin.
Background: Melasma is a dermatosis with significant repercussions on patients' quality of life, and there is currently no standard treatment. Hydroquinone is deemed the treatment of choice, but its safety has been questioned in certain cases.
Aims: To determine the efficacy and safety of a new combination of retinoids in the improvement of melasma.