Exercise training prevents beta-adrenergic hyperactivity-induced myocardial hypertrophy and lesions.

Background: Sustained beta-adrenoreceptor activation promotes cardiac hypertrophy and cellular injury.

Aims: To evaluate the cardioprotective effect of exercise on damage induced by beta-adrenergic hyperactivity.

Methods: Male Wistar rats were randomised into four groups (n=8 per group): sedentary non-treated control (C), sedentary treated with isoproterenol 0.