Publications by authors named "Maria T Mazzucchelli"
Introduction. Therapeutic hypothermia (TH) reduces the risk of death or disability in children with moderate to severe hypoxic ischemic encephalopathy (HIE). Objective.
View Article and Find Full Text PDFIntroduction: Congenital diaphragmatic hernia (CDH) prevalence is low while its associated morbidity and mortality rates are high. Postnatal prognostic factors on the first day of life are useful for predicting the outcome.
Objectives: To determine the mortality predictive ability of postnatal echocardiographic, clinical, and biochemical factors among newborn infants with CDH in their first day of life.
Article Synopsis
- The study investigated the effects of treprostinil on neonates with congenital diaphragmatic hernia and persistent pulmonary hypertension after one week of treatment, focusing on changes in the oxygenation index and other clinical outcomes.
- In a quasi-experimental design, 17 neonates were treated and monitored; results showed significant improvement in oxygenation, with 15 out of 17 patients surviving post-treatment, although some still had severe pulmonary hypertension.
- While treprostinil was generally well tolerated, some patients experienced adverse effects, and it suggested the need for further research to identify which patients might benefit the most from the treatment.