Publications by authors named "Maria T Hojyo-Tomoka"

Background: Actinic prurigo is an idiopathic photodermatosis, the pathophysiology of which has been hypothesized to involve subtype IV type b (Th2) hypersensitive response, whereby IL4, IL5, and IL13 are secreted and mediate the production of B cells, IgE, and IgG4.

Objectives: To examine the association of serum IgE levels and the clinical severity of injuries.

Methods: This case-control study comprised patients with a clinical and histopathological diagnosis of actinic prurigo, as well as clinically healthy subjects, from whom 3cc of peripheral blood was taken for immunoassay.

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Article Synopsis
  • Actinic prurigo is a skin condition mainly seen in indigenous and mestizo Latin American populations, characterized by itchy skin and mucosal lesions that worsen with sun exposure and typically begins in childhood.
  • The exact cause is not well understood, but it involves an unusual immune response with high levels of certain immune cells, hinting at a hypersensitivity reaction.
  • Diagnosis is based on clinical observation and specific histopathology findings, while thalidomide is currently the most effective treatment available despite potential side effects.
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Background: Actinic prurigo (AP) is an idiopathic photodermatosis that usually onsets during childhood and predominates in women. It is characterized by the symmetrical involvement of sun-exposed areas of the skin, lips, and conjunctiva.

Objectives: This study aimed to analyze the risk factors associated with AP using a case-control design.

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Aplasia cutis congenita is a rare condition characterized by the absence of skin and sometimes other underlying structures such as bone or dura. It can be a part of various syndromes and can be associated with multiple genetic diseases, malformation patterns, or a combination of all. It is even considered as a form frustre of a neural tube defect in several literatures.

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Background: Treatment options for cutaneous striae are very limited.

Objective: To determine if subcision is an effective treatment for cutaneous striae and compare a combination with 0.1% tretinoin cream against a single treatment.

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Objective. This study describes the clinicopathologic features and therapeutic results of 116 patients with actinic prurigo cheilitis seen over an 11-year period. Study Design.

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