Publications by authors named "Maria T Camacho"
Pharmacol Res
January 2004
Article Synopsis
- Phosphodiesterase inhibitors like aminophylline were tested for their ability to reduce inflammation and improve endothelial function during endotoxemia in a rat model.
- The study involved administering aminophylline and endotoxin to different groups of anesthetized rats while monitoring their gas exchange, blood pressure, and heart rate over 6 hours.
- While aminophylline did not prevent the adverse effects of endotoxemia during sepsis, it showed some improvement in acid-base balance in control rats, suggesting further research is needed to explore effective dosages.
