Publications by authors named "Maria Stoyanova"

Background: The COVID-19 pandemic has brought significant mental health challenges, particularly for vulnerable populations, including non-binary gender individuals. The COMET international study aimed to investigate specific risk factors for clinical depression or distress during the pandemic, also in these special populations.

Methods: Chi-square tests were used for initial screening to select only those variables which would show an initial significance.

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Background: The prevalence of medical illnesses is high among patients with psychiatric disorders. The current study aimed to investigate multi-comorbidity in patients with psychiatric disorders in comparison to the general population. Secondary aims were to investigate factors associated with metabolic syndrome and treatment appropriateness of mental disorders.

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In this study, we present the synthesis of five novel compounds by combining flurbiprofen with various substituted 2-phenethylamines. The synthesized derivatives underwent comprehensive characterization using techniques such as H- and C-NMR spectroscopy, UV-Vis spectroscopy, and high-resolution mass spectrometry (HRMS). Detailed HRMS analysis was performed for each of these newly created molecules.

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Article Synopsis
  • A large international study involving 55,589 participants from 40 countries was conducted to assess the impact of COVID-19 on mental health, revealing that 17.80% of participants experienced probable depression and 16.71% reported distress.
  • The research indicated that individuals with a history of mental disorders showed significantly higher rates of depression, with the highest risk linked to conditions like Bipolar disorder and self-harm, and found that belief in conspiracy theories was prevalent among participants.
  • The study developed a model demonstrating the connection between anxiety, distress, and the progression to probable depression and suicidality, suggesting that addressing modifiable factors could be beneficial in improving mental health outcomes.
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In this study, Bi2O3-Co3O4 composite oxides were prepared and their catalytic efficiency to activate peroxymonosulfate (PMS) towards the degradation of Acid Orange 7 dye (AO7) was evaluated. The characterization of the synthesized catalysts was carried out by XRD, TEM, XPS, FT-IR, and ICP-OES analyses. The increased basicity of the Bi2O3-Co3O4 hybrids contributed to the much better catalytic activity in PMS activation resulting in a considerably higher rate of AO7 degradation compared to that obtained with bare Co3O4.

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Background: Premenstrual syndrome (PMS) and its more severe form premenstrual dysphoric disorder (PMDD) are highly prevalent conditions, but there seems to be ethnic and cultural variances in their distribution.

Aims: To explore the prevalence of PMS/PMDD and their typical clinical features in a Bulgarian population.

Materials And Methods: This investigation was designed and executed as a cross-sectional descriptive study.

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Combining a successful career with family planning has become increasingly important in recent years. However, maintaining a relationship, deciding upon the optimal time for pregnancy and other family planning decisions can still be quite challenging, especially for junior doctors whose training is long and demanding. Currently, women form an important part of the medical workforce, and there is noticeable feminization in migration.

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Introduction: Access to mental health (MH) services is unequal worldwide and changes are required in this respect.

Objectives: Our aim was to identify the delay to the first psychiatry consult and to understand patients' characteristics and perspectives on the factors that may influence the delay, among a sample of participants from three Southeastern European Countries.

Materials And Methods: The WHO Pathway Encounter Form questionnaire was applied in 400 patients "new cases" and a questionnaire on the factors influencing the access was administered to the same patients, as well as to their caretakers and MH providers.

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In the present study bulk NiO(x) and supported NiO(x)/ZrO(2) catalysts have been prepared. The bulk NiO(x) was synthesized using the precipitation-oxidation method with reverse order of precipitation while deposition-precipitation technique was used for the preparation of zirconia supported catalyst. The as-prepared samples were characterized by means of XRD, HRTEM, SAED, IR-spectroscopy, and chemical analyses.

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Introduction: There are a lot of unresolved issues associated with the classification, diagnosis, clinical management and understanding of the underlying pathogenic mechanisms of bipolar affective disorder.

Aim: To search for discrete endophenotypes in BAD.

Subjects And Methods: We studied various bipolar I and II and recurrent depression patient samples and healthy controls using descriptive data, self and clinician-rated scales for neurological and psychopathological symptoms, neurocognitive instruments, and inventories for temperamental and characterological features.

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